abstract |
(57) [Summary]nA first nucleic acid encoding a heterologous polypeptide, wherein at least one codon of the mRNA transcribed from said first nucleic acid has been replaced with codon UGA, and a second nucleic acid operably linked to said first sequence , Wherein the second nucleic acid is capable of directing translation of the UGA codon as selenocysteine, comprising the step of regulating the expression of a heterologous protein in vivo and in vitro. .. |