http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H08509237-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D243-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D243-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 |
| filingDate | 1994-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1996-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H08509237-A |
| titleOfInvention | 1,5-benzodiazepines useful as gastrin or CCK antagonists |
| abstract | (57) [Summary] A compound of the following formula (I) having gastrin and / or CCK-B antagonist activity and a pharmaceutically acceptable salt thereof. (In the formula, R 1 represents a C 3-7 cycloalkyl, a C 7-11 bridged cycloalkyl or a C 1-6 alkyl group (these alkyl groups are hydroxy, C 1-4 alkoxy, phenyl, C 1-6 Alkoxycarbonyl, C 3-7 cycloalkyl or C 7-11 bridged cycloalkyl group may be substituted), R 2 represents a substituted or unsubstituted phenyl group (substituent is 1 or 2 halo, C 1 -4 alkyl, nitro, cyano, trifluoromethyl, trifluoromethoxy, C 1-4 alkylthio or (CH 2 ) n R 4 where R 4 is hydroxy, C 1-4 alkoxy, CO 2 R 5 , NR 5 R 6, SO 2 NR 5 COR 7, CONR 5 or a SO 2 R 7 or R 4, represents tetrazole, the carboxamide tetrazole or 3-trifluoromethyl-1,2,4-triazole group, These groups may be substituted by C 1-4 alkyl group at one of the nitrogen atom), R 3 is C 3-7 cycloalkyl, C 7-11 bridged cycloalkyl or C 1-6 alkyl (Wherein these alkyl groups may be substituted with phenyl, C 3-7 cycloalkyl or C 7-11 bridged cycloalkyl groups), R 5 represents hydrogen or a C 1-4 alkyl group, and R 6 represents Independently represents hydrogen, a C 1-4 alkyl group or a group SO 2 CF 3 , R 7 represents C 1-4 alkyl, R 8 represents hydrogen or a halogen atom, m is 0, 1 or 2. , X represents oxygen or NH, and n is 0 or 1.) |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010113458-A1 |
| priorityDate | 1993-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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