abstract |
(57) [Summary] The present invention provides (a) (i) a safe and effective amount of a zinc ion source; (ii) a citrate ion source; and (iii) pyrophosphoric acid, phosphonic acid, diphosphonic acid and a general formula: (P n O (3n + 1) ) (n + 2)- (n is an integer of 2 to 21), one or more anticalculus agents selected from the group consisting of pharmaceutically acceptable linear condensed polyphosphoric acid ( The zinc: citric acid molar ratio is at most about 1: 1 and the zinc: pyro molar ratio is at most about 1: 1); and (b) comprising a pharmaceutically acceptable topical oral carrier. It relates to a composition for treating or preventing dental plaque, tartar, gingivitis or halitosis in the oral cavity. The present invention also relates to a method of treating or preventing oral plaque, tartar, gingivitis or halitosis, which comprises administering such a composition to the oral cavity of a human or other animal. |