http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H08503949-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-487 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B57-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B55-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-487 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C57-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-64 |
filingDate | 1993-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1996-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-H08503949-A |
titleOfInvention | Selective crystallization of α-aryl carboxylates |
abstract | (57) [Summary]nA method for producing S (+)-ibuprofen L-lysinate salt or R (-)-ibuprofen L-lysinate salt by selective precipitation from a mixture containing the enantiomer of ibuprofen and L-lysine is provided. The amount of L-lysine is about molar equivalent or less than the amount of one enantiomer in the ibuprofen enantiomer mixture. When one of the ibuprofen enantiomers is precipitated from the mixture, the entire precipitate and reaction mixture is held at the second temperature for a sufficient time to dissolve the first precipitate in the reaction mixture again, The ibuprofen enantiomer of is precipitated from the mixture in salt form. If necessary, the active ibuprofen is racemized by heating at 100-300 ° C in the substantial absence of other substances. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008297281-A |
priorityDate | 1992-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 195.