http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H08502059-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J73-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J73-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J73-00 |
| filingDate | 1993-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1996-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H08502059-A |
| titleOfInvention | Novel 17β-substituted-4-azaandrostane derivative, pharmaceutical composition containing them and method for producing the same |
| abstract | (57) [Summary] The present invention provides compounds represented by the general formula (I): [In the formula, R is hydrogen or a C 1-3 alkyl group; R 1 and R 2 are the same or different and represent hydrogen or a C 1-4 alkyl group. However, both can mean hydrogen only when n is greater than 5; or R 1 and R 2 both represent an α, ω-alkylene group containing 5 to 7 carbon atoms, Are bonded to the same ring member carbon atoms, n is 4,5, 6 or 7; and ---- the bond line represents a single bond or a double bond]. It relates to a 17β-substituted-4-azaandrostane derivative. Furthermore, the present invention relates to a pharmaceutical composition containing these compounds and a method for producing a compound represented by the general formula (I). The compounds of general formula (I) exhibit a 5α-reductase enzyme inhibitory action and therefore their purpose is to reduce the concentration of dihydrotestosterone in tissues, benign prostate hypertrophy, acne, seborrhea, It is beneficial in the treatment of all diseases such as hirsutism and androgenic alopecia. |
| priorityDate | 1992-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 125.