Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S930-12 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-49 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-91 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-22 |
filingDate |
1993-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
1996-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-H08500010-A |
titleOfInvention |
Platelet-derived growth factor antagonist |
abstract |
(57) Summary The present invention describes antagonists to PDGF. Antagonists include amino acids and may be monomeric or dimeric. Particularly preferred are dimers that bind the PDGF receptor but block dimerization of the bound receptor. Dimerization is necessary for the PDGF or antagonist effect. Nucleic acid sequences that make antagonists and cell lines infected with the substance have also been described. The figure shows the amino acid sequences of peptides eluted from the PDGF-A HPLC experiments. |
priorityDate |
1992-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |