| abstract |
(57) [Summary] [Structure] Porphyromonas gingivalis type I A peptide (comprising at least 5 consecutive amino acid residues) corresponding to a fragment derived from the amino acid sequence of 72KD a subunit protein constituting I fimbria, or a derivative thereof or a salt thereof. Furthermore, a composition for diagnosing periodontal disease comprising these peptides, a periodontal disease preventive vaccine, and use of an antibody obtained by immunizing an animal with such peptides for preventing or treating periodontal disease. [Effect] Not only can the diagnosis of a certain periodontal disease be easily performed using the peptides themselves, When it is used in combination with the peptides corresponding to the fragment constituting the type I pili of the bacterium, the pathological condition of periodontal disease can be more accurately specified. |