| abstract |
(57) [Summary] A corneal therapeutic agent capable of promoting corneal healing after corneal refractive surgery and preventing corneal opacity. The therapeutic agent for cornea of the present invention contains at least one kind of hexapeptide represented by the following formula (I) or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable carrier. AB-Pro-CDE (I) [In the formula, A represents arginine or lysine in which the N-terminal amino group is deaminated, alkylated or acylated, B represents arginine, lysine or histidine, and Pro Represents proline, C represents tyrosine, tryptophan or phenylalanine, D represents valine, isoleucine or leucine, and E represents a C-terminal carboxyl group of -C. OOR, —CH 2 OR or —CONHR (R is C 1 to Represents a C 4 alkyl group, R is a hydrogen atom or C 1 to C 4 Represents an alkyl group) of valine, isoleucine or leucine] |