| abstract |
(57) [Summary] [Structure] General Formula (I) [In the formula, R is H, a methyl or amino group, Q is CH, C F, CCl, COH, CCH 3 , COCH 3 or N, R 1 Is cyclopropyl, ethyl, a phenyl group substituted with one or more F, R 2 is, for example, H, linear or branched C 1-4 alkyl, R 3 and R 4 are each independently To H Alternatively, it is C 1-3 alkyl or the like. ] A quinoline (naphthyridine) carboxylic acid derivative represented by the following, a pharmacologically acceptable non-toxic salt, an ester that can be easily hydrolyzed in vivo, Solvates and isomers. [Effect] Not only has an excellent antibacterial action and a broad antibacterial spectrum, but also exhibits excellent pharmacokinetic properties. |