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publicationDate 1996-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H0838192-A
titleOfInvention Monoclonal antibody-producing cell, method for producing the same, monoclonal antibody and method for producing the same
abstract (57) [Summary] [Structure] In a method for producing an antibody-producing cell that produces a monoclonal antibody having specific reactivity to a protein, immunization is induced with either a native protein or a denatured protein, and then A method for producing a monoclonal antibody-producing cell characterized by fusing an antibody-producing cell obtained from an animal boosted with the other protein with a myeloma cell, a monoclonal antibody-producing cell obtained by this production method, and this monoclonal antibody A method for producing a monoclonal antibody, which comprises culturing antibody-producing cells, and a monoclonal antibody produced by this method. [Effect] Among the proteins, it is possible to efficiently produce a protein for which it was difficult to produce a monoclonal antibody by the conventional method. The obtained monoclonal antibody is useful for various diagnostic methods and various reagents for specifically detecting the target protein, and also useful as a medicine. The obtained antibody-producing cells are also useful as a source of antibody genes in addition to producing the above-mentioned antibody.
priorityDate 1994-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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