http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H08333360-A

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_983fa366d54b080542742d72951c002c
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4427
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12
filingDate 1995-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_04f5d180fa318ad06e56a1d2d80b1228
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b4f454ac38b89460477efdc551fb84c
publicationDate 1996-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H08333360-A
titleOfInvention Method for producing naphthamide derivative
abstract (57) [Summary] [Structure] General formula [Chemical formula 1] (In the formula, n is 1 to 6) and a 3,5-dihydroxynaphthoic acid derivative represented by the general formula R 2 COX (III) (wherein R 2 is a substituted or unsubstituted carbon number 1 to 5 is an alkyl group of 5 and X is a halogen atom), and is reacted with an acyl compound represented by the following general formula: (In the formula, R 2 is the same as the above, R 1 is a hydrogen atom or a group represented by R 2 CO—, and R 2 is the same as the above.) After the compound is obtained, the mixed acid anhydride compound is then reacted with 1- (2-aminoethyl) -4-benzhydrylpiperidine to give a compound of the general formula: (In the formula, R 1 is the same as the above, and n is the same as the above.) In the method for producing the naphthamide derivative. [Effect] This method is useful as an industrial production method because the naphthamide derivative represented by the general formula (I) useful as a drug such as an antiallergic agent can be produced in high yield.
priorityDate 1995-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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