abstract |
(57) [Summary] (Modified) [Problem] To provide an excellent quinolone synthetic antibacterial drug. SOLUTION: The following formula (I) (In the formula, a is 0 or 1, b is an integer from 2 to 5, and c is Is 0 or 1, d is an integer from 0 to 2, and Z is An oxygen atom or a sulfur atom, R 1 is a hydrogen atom, an amino group, A monoalkylamino group having 1 to 6 carbon atoms, a dialkylamino group each having 1 to 6 carbon atoms independently, a hydroxyl group, an alkoxyl group having 1 to 6 carbon atoms or a hydroxyalkyl group having 1 to 6 carbon atoms, R 2 Is a hydrogen atom, an alkyl group having 1 to 6 carbon atoms, a hydroxyalkyl group having 1 to 6 carbon atoms, a halogenoalkyl group having 1 to 6 carbon atoms, a formyl group or an alkylcarbonyl group having 2 to 7 carbon atoms, and R 3 is hydrogen. Represents an atom or an alkyl group having 1 to 6 carbon atoms. ) Spiro compounds represented by the formula) and salts thereof. |