| abstract |
(57) [Summary] [Structure] Formula (1); (In the formula, R 1 represents a hydrogen atom or a lower alkyl group, and R 1 2 , R 3 , R 4 and R 5 are the same or different and each represents a hydrogen atom, a halogen atom, a nitro group, a lower alkyl group, a lower alkoxyl group or a substituted or unsubstituted phenoxy group, and X is a substituted or unsubstituted Represents an aromatic hydrocarbon group or a substituted or unsubstituted heterocyclic group, Y represents a substituted or unsubstituted aromatic hydrocarbon group, a substituted or unsubstituted heterocyclic group, a substituted or unsubstituted aromatic hydrocarbon group A substituted carbonyl group, a carbonyl group substituted with a substituted or unsubstituted heterocyclic group, or an N, N-disubstituted carbamoyl group), which is a ketonitrile derivative or a salt thereof as an active ingredient. [Effect] It has excellent antibacterial activity against Gram-positive and Gram-negative bacteria. |