abstract |
(57) Abstract: An object of the present invention is to provide an anti-atherogenic agent having excellent ACAT inhibitory activity. SOLUTION: General formula: [Wherein R 1a is C 1-12 alkyl, cycloalkylalkyl; R 1b is the same group as H and R 1a ; R 2a , R 2b , R 2c And R 2d is H, OH, NH 2 , CN, nitro, C1-1. 2 alkyl, F-substituted alkyl, C1-10 alkoxy, Aralkyloxy, alkylthio, alkylsulfinyl, alkylsulfonyl, hydroxyiminomethyl, halogeno, alkylamino, methylenedioxy for R 2a and R 2b , etc .; R 3 is C 1-6 alkyl; R 4 is hydroxyalkyl, etc .; n is 0 or [1] Compounds and salts thereof. |