abstract |
(57) Abstract: A novel intermediate for producing a steroid having a spiro ring at position 17 is provided. SOLUTION: General formula (IV): [Wherein R 1 has an optionally substituted carbocyclic or heterocyclic aryl or aralkyl group (however, optionally substituted alkynylphenyl group is excluded), R 2 at α-position or β-position indicates a hydrocarbon group having 1 to 18 carbon atoms, the wavy line of spiroether indicates that an oxygen atom can be present at α-position or β-position, and the dotted line has this Indicating that there may be a second bond between the carbons, and K represents a protecting group for the ketone]. |