| abstract |
(57) [Summary] (Modified) [Objective] To provide a therapeutic agent for stress-related disorders, which comprises a corticotropin-releasing factor (CRF) antagonist as an active ingredient. [Structure] [4- (7-methoxyquinolin-8-ylmethyl) -5-methylsulfanyl-2- (2,4,6- Trichlorophenyl) -2H-pyrazol-3-yl] -Dimethylamine; dibutyl- [6-methyl-3-methylsulfanyl-1- (2,4,6-trichlorophenyl) -1H-pyrazolo [3,4-d] pyrimidine-4- Yl] -amine; 4- (1-ethyl-propyl) -2, 5,6-Trimethyl-7- (2,4,6-trimethylphenyl) -7H-pyrrolo [2,3-d] pyrimidine; Agent. |