abstract |
(57) Abstract: A novel pyridine compound having a high affinity for a melatoninergic receptor and useful for the treatment of sleep disorders, a method for producing the same, and a pharmaceutical composition containing the same. provide. SOLUTION: Formula (I): [In the formula, R 1 , R 2 , R 3 and R 4 are hydrogen, halogen, alkyl, alkoxy and the like; R 5 is a group represented by the formula —AB— Y {in the formula, A is C 1 -C 6 alkylene, B is a group -N (R 6) C (= Z ) -, - N (R 6) C (= Z) -NH - or -C (= Z) N (R 6) - Table by (wherein, R 6 is hydrogen, alkyl etc., Z is oxygen or sulfur and which) is, Y represents hydrogen, and the like or alkyl} Done; X Is oxygen, sulfur or a group -N (R 7) (wherein, R 7 is Hydrogen, alkyl, etc.], a method for producing the same, and a pharmaceutical composition containing the same. |