| abstract |
(57) [Summary] (Modified) [Problem] Diseases associated with melatonin activating system, particularly periodicity, because it has a high selective affinity for melatonin receptor and is active in melatonin activating system. Provided is a pharmaceutical composition which is effective in treating depression, sleep disorders, cardiovascular diseases, insomnia and fatigue due to changes in time zones, appetite disorders, and obesity. A general formula I, for example formula III , A process for producing the same, and a pharmaceutical composition containing the same. |