| abstract |
(57) [Summary] (Modified) SOLUTION: A recombinant gene for producing a transgenic animal, comprising a gene promoter, a heat shock protein 70 gene attached downstream of the gene promoter, and the transgenic animal. A transgenic mouse having a recombinant gene for production and expressing a desired trait. In addition, a recombinant gene containing a gene promoter and a heat shock protein 70 gene attached downstream of the gene promoter is inserted into a fertilized egg, and the fertilized egg is transferred to a surrogate mother mouse, reared and delivered, and A method for producing a transgenic mouse, which comprises a step of obtaining an ancestor mouse that is an offspring mouse in which the trait is expressed, and a transgenic mouse produced by this production method. [Effect] It can be usefully used in research fields such as lifesaving before the development of autoimmune diseases, development of immunosuppressive agents, and new drug assay system. |