| abstract |
(57) Abstract: [PROBLEMS] To provide an immunoassay reagent containing an anti-cannabinoid antibody having wide specificity, recognizing as many major metabolites of the active ingredient THC of marijuana as possible. SOLUTION: The following formula (1) including a chemical linker that facilitates conjugation with a protein (In the formula, R 1 is an alkyl group, R 2 and R 3 are lower hydrocarbon groups each optionally having a substituent, and a, b and c are each a single bond or a double bond.) And conjugating it to a protein carrier to prepare an immunogen, administering the immunogen to an animal, and averaging at least about 80% of all major THC metabolites from splenocytes of the immunized animal. An anti-cannabinoid antibody having reactivity is obtained. |