abstract |
(57) [Summary] [Structure] A skin lightening agent comprising Naocol-A or isonaocol-D 1 represented by the general formula (1), and a skin cosmetic containing the compound. Embedded image [For Naokol-A, X is OH, W is CO, R 1 and R 2 Is H, Y is a group of the following formula (2), isonaocol-D 1 is X is OH, W is CH—OH, R 1 and R 2 are bonded together to represent a single bond, and Y is the following formula (3) )]] [Effects] Naocol (1) has an excellent melanin pigmentation preventing / ameliorating effect by suppressing the melanin production of melanocytes, and the skin cosmetics containing it exhibit an excellent skin whitening effect, and are effective for the stains caused by sunburn etc. It is also extremely useful for the prevention and treatment of freckles. |