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filingDate 1994-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98a75db7838cd70e46fc412d9a3c2084
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publicationDate 1996-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H08277-A
titleOfInvention Production of optically active benzothiazepines by enzymatic reaction
abstract (57) [Summary] [Structure] General formula [II]: (In the formula, ring A and ring B represent a benzene ring which may have a substituent. R represents hydrogen or di (lower alkylamino) lower alkyl group.) A general formula [I] characterized by acting an asymmetric reductase: (In the formula, symbols have the same meanings as described above) A process for producing an optically active 1,5-benzothiazepine compound. According to the present invention, an optically active 1,5-benzothiazepine compound [I] can be efficiently produced from the above compound [II] by a one-step enzymatic reaction.
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