| abstract |
(57) [Summary] [Structure] General formula [I] [However, Ar is an aryl group, OZ is a hydroxyl group which may be protected, R is a β-D-glucopyranosyl group or 4- Represents an O- (α-D-glucopyranosyl) -β-D-glucopyranosyl group (provided that OZ is a hydroxyl group and R is β; When it is a -D-glucopyranosyl group, it excludes a group in which Ar is a hydroxyphenyl group, a lower alkoxyphenyl group or a phenyl group). ] A hypoglycemic agent containing a dihydrochalcone derivative or a pharmacologically acceptable salt thereof as an active ingredient. [Effect] Since the hypoglycemic agent of the present invention exhibits a urinary glucose increasing action and a hypoglycemic action based on inhibition of glucose reabsorption in the kidney, it is useful as a therapeutic / preventive agent for diabetes. |