| abstract |
(57) [Summary] [Purpose] To enhance the activity of pyripyropene to inhibit acylcoenzyme A cholesterol acyltransferase. [Structure] A compound represented by the following formula: [Wherein R 1 is O together with OH, an acyl group or R 1 ′, R 1 ′ is H, or together with R 1 is O, R 2 is H (in this case, between the 5th and 13th positions: Double bond), OH, or R 2 ' Together with O, R 2 'represents H or R 2 together with O, or a bond at the 5-position, and Ac represents an acetyl group]. |