http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H08268988-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dfd617dc43a4c986d2dd81e4cb39d9dd |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-165 |
| filingDate | 1995-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e13eebe6446c5223cf08bc5bc573141 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5cc1e0f268e4a82e487084537e09fb6d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_353ff144ec186ae032751ae61b073b66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58f4d15e1e8a691a4778b3340454b43e |
| publicationDate | 1996-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H08268988-A |
| titleOfInvention | Aminobenzamide compound and its production method |
| abstract | (57) [Summary] [Objective] 3- [2- (3,4-dimethoxyphenyl) ethylcarbamoylmethyl] amino-N-methylbenzamide [final compound], which is useful as an anti-ulcer drug and an effect of improving indefinite complaints Regarding the production method, it is an object of the present invention to provide an industrial production method and a synthetic intermediate thereof, which uses a solvent non-toxic to the human body and produces a small amount of by-products. [Structure] (1) As a synthetic intermediate (iodoacetyl) Provide -3,4-dimethoxyphenethylamine. (2) N- (chloroacetyl) -3,4-dimethoxy is acetylated to 3,4-dimethoxyphenethylamine in the presence of a ketone or alcohol, which is sparingly soluble in water and liquid at room temperature. Phenethylamine is produced, and then the product is reacted with hydroiodide under the same solvent to produce N- (iodoacetyl) -3,4-dimethoxyphenethylamine. A method for producing the above-mentioned final compound which is crystallized via a monohydrate by reacting with amino-N-methylbenzamide. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008247753-A |
| priorityDate | 1995-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 73.