| abstract |
(57) [Summary] [Structure] A pathogen infection-preventing agent containing, as an active ingredient, a microorganism belonging to the Lactobacillus acidophilus complex and having an affinity for asialo GM1, or a bacterium thereof. A protein which can be extracted from the microbial cells of the above-mentioned microorganism using an aqueous alkaline salt solution or a surfactant, has an affinity for asialo GM1, and has a pathogen infection protective activity. The pathogen is asialo GM1 And a microorganism belonging to the pathogenic E. coli, Pseudomonas aeruginosa, Pseudomonas cepacia, Campylobacter, rotavirus, reovirus or poliovirus. [Effects] The infection protective agent of the present invention containing the microorganism or its bacterial cell as an active ingredient is effective as an infection protective agent against the pathogen. The protein of the present invention is also very effective as a protective agent against infections against the above pathogens. further, The active ingredient of the present invention is used as a lactic acid bacterium in a large amount in foods and the like, and has extremely high safety. |