| abstract |
(57) [Summary] [Constitution] Siaα2,3Galβ1,4GlcNAcα2,8-sialyltransferase O3 specified by the amino acid sequence shown in SEQ ID NO: 1 in the sequence listing; and a gene encoding the sialyltransferase O3 . [Effect] Siaα2,3Galβ1,4GlcNAc has α2,8-sialyltransferase activity, for example, a reagent that introduces a sugar chain having polysialic acid or oligosialic acid into a protein; heritability lacking a specific sugar chain It is useful as a medicament for treating a disease; a medicament for suppressing cancer metastasis, suppressing an inflammatory reaction, and activating nerve tissue, and the like. |