| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_97ddd4d1d0ebc8a7d2c8e7d214d08cf3 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-91 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64 |
| filingDate |
1994-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a4994bfd7622aacdbad2d1e2a21daa5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b82188a61743c346773619ba023466e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d114d3184763af4a7ebacf9d24c608c3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78fd82727afb635c9ce3d8d6e65bd668
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a58647121cf12d656d3cbebd0d8a28ed
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8825de272fc220dad9c97730bd87cbc2 |
| publicationDate |
1996-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-H0823972-A |
| titleOfInvention |
Glucagon-degrading enzyme, gene encoding the same, and antibody to the glucagon-degrading enzyme |
| abstract |
(57) [Summary] [Structure] A glucagon-degrading enzyme having the following enzymatic properties, a gene encoding the same, and an antibody against the glucagon-degrading enzyme. (1) Action: Glucagon, vasoactive intestinal peptide and secretin are used as substrates and hydrolyzed. (2) Isoelectric point: pI 6.8 (3) Inhibitor: Inhibited by 1 mM antipain, not 1 mM leupeptin and 0.1 mM pepstatin. (4) Molecular weight: 83 kDa (by SDS electrophoretic method) [Effect] The glucagon-degrading enzyme of the present invention has an action of degrading glucagon and VIP (vasoactive intestinal peptide), and excess glucagon and VI It is expected to be effective in treating and preventing various diseases caused by the presence of P. |
| priorityDate |
1994-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |