abstract |
(57) [Summary] (Modified) [PROBLEMS] To provide a new method for synthesizing ω-hydroxy acids, which uses a commercially available starting material and reduces the production cost. A method for producing a w-hydroxy acid of the general formula V, in which an aliphatic acyl group is coupled by enamine chemistry, followed by ring expansion and selective reduction of a keto acid. (A is an integer of 1-20, b is an integer of 2-40, c is an integer of 1-30, and d is an integer of 2-60) |