abstract |
(57) Abstract: Tumor growth inhibitory factor (TIF), in particular substantially purified, capable of inhibiting the growth of certain tumor cells without adversely affecting the growth of certain normal human cells. To provide a modified polypeptide factor. The TIF of the present invention does not suppress the proliferation of TGF-dependent normal cells. Also, in the present invention, at least two different TIFs have been isolated, substantially purified and confirmed. Not only are they different from the prior art, but they are also distinguishable from each other. Previously known TIF Unlike, the TIFs of the present invention have novel mitogenic properties and human cell growth stimulating properties. |