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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-08
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filingDate 1995-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cfb0a1924cc08b1c79a66ee6d0536b1b
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publicationDate 1996-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H08231587-A
titleOfInvention Metal chelate-forming peptide, use thereof and method for producing the same
abstract (57) [Abstract] [PROBLEMS] Chelate with a radioactive metal nuclide easily and stably without the need for treatment such as heating, and the radiometal nuclide labeled product does not show non-specific accumulation in biodistribution. Provided are a metal chelate-forming peptide, its use, and its production method. The amino acid sequence is X1 in order from the N-terminal side. A metal chelate-forming peptide consisting of 3 amino acid residues of X2-Cys, a complex in which a physiologically active substance is bound to the peptide, a compound in which a radioactive metal nuclide is coordinated to the peptide and the complex, and the compound The radioactive diagnostic agent and radioactive therapeutic agent are However, X1 is Cys X2 is any amino acid residue except a residue, Cys residue and Pro residue. Further, the N-terminal, C-terminal and side chain functional groups of the chelate-forming peptide may be substituted with a protecting group and the like, and each amino acid residue may be either D-form or L-form.
priorityDate 1994-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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