| abstract |
(57) Abstract: [PROBLEMS] To provide a composition for topical application to human skin, hair or nails that have been aged and / or photodamaged, and a method for producing the composition. Lactate dehydrogenase inhibitors stimulate epidermal keratinocyte proliferation and collagen synthesis in skin tissue. The inhibitor is preferably pyruvic acid, acetic acid, Acetoacetic acid, β-hydroxybutyric acid, Krebs cycle pathway metabolite, aliphatic saturated or unsaturated fatty acid containing 8 to 26 carbon atoms, ω-hydroxy acid containing 22 to 34 carbon atoms, glutamic acid, glutamine, valine , Alanine, Used with co-active ingredients such as leucine and mixtures thereof. |