http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H08225525-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bd2cb78eb65f8129f9f6b7c05a155a92 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-52 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J27-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J27-122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 |
| filingDate | 1995-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ccafbdb8162e5d30a1a08bd16d02b85c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1792a438bc5c2e7d5dbf8211020cce3f |
| publicationDate | 1996-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H08225525-A |
| titleOfInvention | Method for producing oxindoles |
| abstract | (57) 【Abstract】 PROBLEM TO BE SOLVED: Industrially with high purity and high yield of oxindoles using 2-halogenophenylacetic acid, which is relatively easily available, as a starting material in one pot without complicated steps. To provide a method of manufacturing. SOLUTION: Formula (I): (In the formula, X 1 represents a chlorine atom or a bromine atom, Z represents a hydrogen atom, a halogen atom, an alkyl group or an alkoxy group, R represents a hydrogen atom, an alkyl group or an alkoxy group, M 1 represents a hydrogen atom, An ammonium group or an alkali metal, X 1 and Z may be the same or different, and n 1 represents an integer of 1 to 4) and the presence of a copper salt catalyst in 2-halogenophenylacetic acid or a salt thereof. Then, a mixture of 2-aminophenylacetic acid or a salt thereof and the oxindole represented by the formula (II) is heated in the presence of an acid catalyst to react 2-aminophenylacetic acid or a salt thereof with lower ammonia. Formula (II) for ring closure (In the formula, Z, R and n 1 have the same meanings as in formula (I).) A method for producing oxindoles. |
| priorityDate | 1994-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 85.