abstract |
(57) Abstract: The present invention provides a therapeutic or prophylactic agent for angina, which has an excellent collateral vasodilator effect. SOLUTION: General formula: [W: -O-, -S-, X: -NR 1 -or W:- NR 1 -, X: -O - , - S-; R 1: H, C 1 -C 6 Alkyl, C 1 -C substituted alkyl; R 2, R 3 : H, C 1 -C 6 alkyl, substituted C 1 -C 4 alkyl, aryl, aromatic heterocycle; R 4 : H, C 1 -C 6 Alkyl, substituted C 1 -C 4 alkyl; substituted C 3 -C 8 cycloalkyl optionally having R 5 : N, A: a single bond, C 2 -C 6 thiazolidinone compound or a pharmacologically acceptable salt thereof having an alkylene. |