http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H08217696-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01c1e0bc0628f76dea731cda5a666ca1 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 |
filingDate | 1995-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f2f73f9649c6ff788589a44da4b94a1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a8a0388bff5d0235922eec44f3627e7 |
publicationDate | 1996-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-H08217696-A |
titleOfInvention | Spherical core for spherical granule, spherical granule, and method for producing the same |
abstract | (57) [Summary] [Purpose] The particle size is uniform, the sphericity is high, the capsules can be filled uniformly, and the variation in the amount of the drug can be prevented, and a uniform and strong coating film can be formed on the surface, and the drug can be released. To provide spherical granules suitable for coating for the purpose of control and the like. [Composition] Viscosity in which cellulosic material is dissolved is 50 to 20 While directly applying a vibration with a frequency of 3000 to 40,000 Hz to the polymer solution of 00cP, it was ejected as uniform droplets into the gas phase, The droplets are allowed to fly over a flight distance that makes them nearly spherical, and then contacted with a coagulant to form particles, which are then dried, 90% or more of particles are within ± 20% of the number average particle diameter, the number average particle diameter is 50 to 1000 μm, and the sphericity is 1.2 or less. Further, the outer surface of the spherical granules is spherical granules coated with a coating agent, and these spherical granules are granules as they are, directly packed into capsules, as capsules, or granulated by compression molding with a excipient. Also used as tablets. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-4493769-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2001172430-A |
priorityDate | 1995-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 157.