| abstract |
(57) Abstract: [PROBLEMS] To provide a non-steroidal anti-inflammatory drug with few side effects on the gastrointestinal tract and kidney. SOLUTION: Formula (Ia): (Wherein R 1 is —H, lower alkyl, halo-lower alkyl, acetyl, substituted acetyl, etc .; R 2 and R 3 are Independently, -H, halo, or -CH 3; R 4 is -H, lower alkyl or -CN; R 5 is -H or lower alkyl; R 6 and R 7, independently, -H, Halo, lower alkyl, lower alkoxy or lower alkylthio; and R 8, halo, lower alkyl, halo - lower alkyl, amino, phenyl optionally substituted by such lower dialkylamino, or -Cl or -CH 3 may be substituted, thienyl, pyridyl or furyl) Or a pharmaceutically acceptable salt thereof. |