http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H08208477-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_afd115dec46c157d3739020ebd4d866b |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-455 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4427 |
| filingDate | 1995-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb7ef5f39c0efa182546a6d5b59a5dd2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8caf390c7d388c51a7f6d84c801d2d6e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78d973d9486795a19f65a8165b5aae43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_966e1224243776836a3fc8b4bcb9998e |
| publicationDate | 1996-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H08208477-A |
| titleOfInvention | Vascular endothelial protective agent |
| abstract | (57) [Summary] [Structure] Formula: [Chemical Formula 1] An agent for protecting vascular endothelium, which contains the compound or salt as described above as an active ingredient. R 1 , R 2 , R 3 : alkyl, cycloalkyl, etc., R 4 , R 5 : H, halogen, nitro and the like (R 4 and R 5 are not H at the same time), X: vinylene, azomethine, A: alkylene, B: —N (R 6 ) (R 7 ) or a group: ] (R 6 , R 7 , R 8 : H, alkyl, etc., Ar: aryl, pyridyl, n: 0, an integer of 1 or 2) [Effect] The compound or salt has extremely low toxicity and has an action of protecting vascular endothelium, It has an action of maintaining the endothelial function at the level of normal blood pressure, and is useful for the treatment and prevention of vascular endothelial damage, particularly vascular endothelial damage associated with the development / progression of hypertension. |
| priorityDate | 1995-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 58.