abstract |
(57) [Summary] [Objective] To provide a method for producing enamine in an aqueous medium. ## STR2 ## Formula 2 in an aqueous medium containing an acid promoter. The aniline (wherein R and X are as described below) is replaced by a cycloalkanone or -dione 3 (Wherein Y and n are as described below), the compound of formula 1 [In the formula, R is CN, CO 2 H or CO 2 R 1 (in the formula, R 1 Is lower alkyl) and Y is CH 2 or C = O, X is hydrogen, lower alkyl, lower alkoxy, Halogen, hydroxy, nitro, NHCOR 2 (wherein R 2 is lower alkyl) or the formula NR 3 R 4 (wherein R 3 and R 4 are independently hydrogen or lower alkyl) and n is 0, 1 or 2.]. |