http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H08183796-A

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c999fee6428152a996011d506925c2d7
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-072
filingDate 1994-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f8ecaa1117822e07de4b3a540dcac5c8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21d7ff1f7862d752d840bf55708ca68e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5dad737453eab9bc9e02570092c1945
publicationDate 1996-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H08183796-A
titleOfInvention Process for producing α-L-aspartyl-D-amino acid-N- (S) -α-alkylbenzylamide
abstract (57) [Summary] (Modified) [Purpose] α-L-aspartyl-D-amino acid-N- A method for producing (S) -α-alkylbenzylamide is provided. [Structure] Strong acid addition salt of L-aspartic anhydride and D -Amino acid-N- (S) -α-alkylbenzylamide is condensed to give α-of the general formula 1 with good reaction selectivity and high yield. L-Aspartyl-D-amino acid-N- (S) -α-alkylbenzylamide is obtained. Further, the reaction solution was made alkaline, and the excess D-amino acid-N- (S) -α-alkylbenzylamide was extracted and removed in an organic solvent, and the aqueous layer was adjusted to pH 4.5 to 6.5 for crystallization. Α-as crystals L-Aspartyl-D-amino acid-N- (S) -α-alkylbenzylamide is obtained. (R 1 represents a C1-4 alkyl group, and R 2 represents a C1-3 alkyl group.)
priorityDate 1994-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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