abstract |
(57) [Summary] [Structure] Formula (I): [In the formula, R 1 represents an R- or RS- group (R represents a carbon number of 1 to 14 hydrocarbon groups), R 2 is an amino group or a mono- or di-substituted amino group, R 3 is a hydrogen atom or a lower alkyl group, R 4 is a carboxyl group or an esterified carboxyl group or is protected at the 1-position. Group which may have a tetrazol-5-yl group] and a pharmacologically acceptable salt thereof. [Effect] This compound has angiotensin II antagonism and is useful for treating and preventing hypertension, heart failure and the like. |