| abstract |
(57) [Summary] [Structure] 3- (2-benzene such as 3- [2- (4-chlorobenzenesulfonamido) ethyl] -1- (3-pyridylmethyl) indole-5-carboxylic acid represented by the following formula 1 Sulfonamidoalkyl) indole derivatives. Embedded image (In the formula, X represents H, a hydroxyl group, etc., m represents 2 to 4, and R 1 represents formula 2 (n = 1 to 5) or — (CH 2 ) 2 —CO OR 3 (R 3 is H or a lower alkyl group), R 2 is a carboxyl group or the like. ) [Effect] Thromboxane A 2 / Prostaglandin H 2 It has an antagonistic effect and is effective as an antithrombotic agent and an antiallergic agent. |