| abstract |
(57) [Summary] [Purpose] A basic pharmaceutical solution for soft gel filling or two-piece encapsulation or tablet production. [Structure] A pharmaceutically acceptable solution of a basic drug for soft gel filling, two-piece encapsulation, or tablet production, comprising the basic drug and a mixed solvent, wherein the mixed solvent has a weight of the mixed solvent. As a standard, 10 ~ 80% by weight of polyethylene glycol, a solubility-increasing amount of hydrogen ions and 1 to 20% by weight of water, wherein the hydrogen ions partially ionize the basic drug, and the basic drug is free acid in the solution. The above solution characterized in that it is present in dissolved form in both salt forms. |