| abstract |
(57) [Summary] (Modified) [Purpose] To provide a quinazoline derivative or a pharmacologically acceptable salt thereof, which has an adenosine uptake inhibitory action and is useful for preventing or treating inflammation such as myocardial protection and foot edema. To do. [Structure] Formula (I) [Wherein R 2 , R 3 , R 4 and R 5 represent hydrogen, halogen, lower alkyl lower alkanoyl and the like; R 6 , R 7 and R 8 represent hydrogen, halogen nitro, lower alkyl and the like; XY is the formula -N (R < 1 >)-CO- or the formula -N = C (R 9 )-; R 1 and R 9 are hydrogen, lower alkyl, alkenyl, aryl, aralkyl; n is 0, 1 or 2 Represents;] or a pharmaceutically acceptable salt thereof. |