| abstract |
(57) [Summary] (Modified) [Purpose] Novel 4-substituted alkylamino-pyrrolo [2,2] 3-d] pyrimidine derivatives are provided. [Structure] Formula [I] (In the formula, R 1 represents a hydrogen atom, an alkyl group, an aralkyl group or the like, R 2 represents an alkyl group, an aralkyl group or the like, R 2 3 , R 6 represents a hydrogen atom, a C 1 -C 3 alkyl group, R 4 represents a C 1 to C 6 alkylene group, and R 5 represents C 2 to C 6 . Alkylene group C 6, an arylene group of C 6 ~C 10, A and B are O, S, N (R 7 ) (R 7 is H, C 1 To C 3 alkyl group), n is 1 when R 5 is a C 2 to C 6 alkylene group, and n is 1 to 3 when R 5 is a C 6 to C 10 arylene group. Represents an integer. ), A pharmaceutically acceptable acid addition salt thereof, and a pharmaceutical preparation effective for the treatment of hypoxemia, containing the compound or a pharmaceutically acceptable acid addition salt thereof as an active ingredient. |