http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H08127569-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7e7022e391363a3cf3486bf3859ce0a7 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-47 |
| filingDate | 1994-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20e745b418d7623aa79f8386e1c0c1aa |
| publicationDate | 1996-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H08127569-A |
| titleOfInvention | Flucytosine manufacturing method |
| abstract | (57) [Summary] [Structure] 5-Fluorouracil is reacted with a phosphorus-containing chlorine displacing agent to give 2,4-dichloro-5-fluoropyrimidine, and ammonia is allowed to act on it to give 4-amino-2- In the method for producing flucytosine by hydrolyzing chloro-5-fluoropyrimidine and producing flucytosine, 2,4-dichloro-5-fluoropyrimidine is treated with ammonia in toluene to give 4-amino-2-chloro-5- Fluoropyrimidine, then 4-amino-2-chloro-5 A method for producing flucytosine, which comprises producing fluorocytosine by treating fluoropyrimidine with concentrated sulfuric acid for dehydrochlorination and then hydrolyzing it. [Effect] By the production method of the present invention, flucytosine can be produced from 5-fluorouracil in a high yield. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106349169-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103435557-A |
| priorityDate | 1994-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 72.