abstract |
(57) [Summary] [Objective] An amino acid derivative having high cancer metastasis inhibitory activity, cell adhesion inhibitory activity and cell migration inhibitory activity, and a cancer metastasis inhibitor, a cell adhesion inhibitor and a cell migration inhibitor comprising the amino acid derivative as an active ingredient. provide. [Structure] An amino acid derivative represented by the following general formula (I) or a pharmacologically acceptable salt thereof, and a cancer metastasis inhibitor, a cell adhesion inhibitor and a cell migration inhibitor containing the amino acid derivative as an active ingredient. General formula (I) In the formula, X represents a linear or branched alkylene group having 1 to 3 carbon atoms, a cyclic alkylene group having 4 to 8 carbon atoms, or a phenylene group, and V and W are —COOH or —CONH 2 , P 1 and P 2 represent amino acid residues or peptide residues, R 1 and R 2 represent hydroxyl groups or organic groups, and R 3 and R 4 represents a hydrogen atom or an alkyl group. |