| abstract |
(57) [Summary] (Correction) [Constitution] The following formula (I) [In the formula, R 1 and R 2 are independently hydrogen, halogen, or an alkoxy group having 1 to 4 carbon atoms, or integrally formed 3,4-methylenedioxy group, and R is 1 to 8 carbon atoms. Alkyl group, R 3 is hydrogen, an alkyl or hydroxyl group having 1 to 4 carbon atoms, A is a bond by a valence or a methylene group, R 4 and R 5 are independently hydrogen, an alkyl group having 1 to 12 carbon atoms. Or, optionally together with an alkenyl group having 1 to 12 carbon atoms, or an adjacent nitrogen atom, optionally oxygen, sulfur or one nitrogen atom (the latter being phenyl, benzyl or alkyl having 1 to 4 carbon atoms). Forming a 4- to 7-membered ring containing an optionally substituted)]. [Effect] The present compound has valuable anti-ulcer activity and anxiolytic activity without sedation, and is useful as a therapeutic drug. |