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filingDate 1993-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4fbc57d154929b70e00ef087507a35b2
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publicationDate 1995-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H0769908-A
titleOfInvention Brain function improving agent
abstract (57) [Summary] [Structure] A brain function improving agent containing 50% ethanol extract of saffron pistil as an active ingredient. [Effect] Since ethanol is known to cause amnesia in animals, the effect of ethanol on amnestic action was examined as an index using passive avoidance learning in mice as a result of memory acquisition and reproduction. The alcohol extract of saffron pistil showed an excellent effect in preventing the deterioration of memory learning ability due to excessive intake of ethanol. In addition, from a study on the effect on hippocampal long-term potentiation, which is said to be closely related to memory learning, it was also confirmed that this extract shows a dose-dependent significant improvement effect on the hippocampal long-term potentiation inhibitory effect of ethanol. Was done.
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