abstract |
(57) [Summary] [Purpose] It has the effect of significantly inhibiting the growth of cariogenic bacteria Streptococcus mutans and Streptococcus sobrinus and periodontal disease-causing bacteria Porphyromonas gingivalis and Fusobacterium nucleatum. Provided is an anti-caries agent and periodontal disease agent which effectively act on caries and periodontal disease. [Structure] General Formulas (I), (II), and (III) (In the formula, R 1 , R 2 , and R 5 independently represent a hydrogen atom or a hydroxyl group, and R 3 and R 4 independently represent a hydrogen atom, a hydroxyl group, or an acetoxyl group.) It is an anti-caries agent, a periodontal disease agent as an active ingredient, and an oral composition containing the same. |