abstract |
(57) [Summary] [Structure] The present invention has the general formula: [Wherein R 1 is a hydrogen atom or a lower alkyl group, R 2 and R 3 are the same or different and each is a lower alkyl group, R 2 4 is a hydrogen atom or a lower alkanoyl group, X is a sulfur atom or a group N—R 5 (R 5 is a lower alkyl group), Y Represents CH or a nitrogen atom, respectively. ] A condensed ring pyridine derivative represented by the following formula. [Effect] The condensed pyridine derivative of the present invention has an anti-inflammatory effect, It has immunomodulatory action, analgesic action, antipyretic action and the like, and is useful as an immunomodulator, antiphlogistic / analgesic / antipyretic drug, for example, for the treatment and prevention of rheumatoid arthritis, nephritis, psoriasis, systemic lupus erythematosus, low back pain and the like. |